Postdoc Chromatine Biology

At LUMC, as a Postdoctoral Researcher in Chromatin Biology, you contribute to bridging fundamental research with clinical applications. You will focus on investigating the genetic aspects of BAFopathies within a ZonMw-funded project. Your work will involve advanced techniques such as CRISPR and long-read sequencing. You will be part of an international team of dedicated researchers, working together to push the scientific boundaries in this field.

You will join the Department of Human Genetics, led by Prof. Dr. Ir. Silvère van der Maarel, a department with 22 research groups focused on genetic and epigenetic facets of monogenic, multifactorial, and acquired diseases and their clinical translation. The department comprises approximately 220 international staff, including professors, students, research analysts, and researchers in training. You will be based in the Developmental Epigenomics research group led by Dr. Lucia Daxinger, embedded in the ‘Molecular Technology and Informatics for Personalised Medicine and Health’ research line, with a distinct focus on understanding the molecular basis of chromatin anomalies using mammalian cellular models, molecular biology techniques, proteomics, and genome-wide approaches such as single-cell and long-read sequencing.

You are an enthusiastic and driven researcher with a completed (or nearly completed) PhD in molecular biology or a related field. You know how to apply your knowledge effectively within an ambitious, international team, where collaboration, autonomy, and clear communication are essential. You thrive in a dynamic research environment and enjoy contributing to collective success.

At least one peer-reviewed publication as first author.Experience in epigenetics and/or chromatin biology alongside analysis of -omics data (e.g. RNA‑seq, WGBS, ChIP‑seq, ATAC‑seq).Proficiency in bioinformatics languages such as R or Python.Excellent practical skills in molecular biology, including cell culture, PCR, and western blotting.Experience in iPSC culture and differentiation, and preferably CRISPR/Cas9 genome editing.

Driven by health; that's our mission. This applies not only to our patients but also to our employees. We strive to provide a safe, inclusive and equitable work environment, with a focus on talent development and connected leadership. In order to be able to continue to learn and develop, we offer internal and external training. You are also entitled to an end-of-year bonus (8,3%), holiday allowance, sports budget, bicycle scheme, home office allowance and an excellent commuting allowance. Furthermore, as an employee of LUMC, you are also affiliated with the ABP pension fund. This means that 70% of your pension premium is paid by LUMC, leaving you with a higher net salary. Nice, right?

As an academic medical center, LUMC strives to have a workforce that is a good reflection of society. We are committed to the highest quality in health care, education and (international) research, in which diverse perspectives are essential. Sustainability is also a high priority for us: we are committed to a healthy future, not only for people, but also for the planet. In line with these values, we aim to be a creative and inspiring place to work, where everyone feels at home, safe and valued. It's all about who you are and what you bring to contribute, regardless of your background. Together, we work toward a sustainable and inclusive future, both for the people around us and for the world we live in. Together, we are LUMC.