Manufacturing Operator

We are looking for the best Manufacturing Operators for our USP/DSP and Fill and Finish departments in Sassenheim, Netherlands!

Join our fully digital Lenti Viral Vector Facility in Sassenheim, producing vectors for multiple myeloma treatment impacting 160,000 patients worldwide. As we prepare for commercial production in mid-2026, we’re looking for Manufacturing Operators (USP/DSP/F&F) to support cell expansion, virus production, purification, and automated filling under GMP and BSL2 conditions.

Build your career at the forefront of innovation in a collaborative environment, with strong growth opportunities through training, mentoring, and clear career paths

About the departments:

Department: Upstream Processing (USP) The USP department focuses on culturing cells and infecting them with a virus. The team operates on regular weekday shifts now, but that will change later this year. Core tasks include: Culturing and inoculation of cells in Shaker Flasks and Wave bags (e.g. cell count, dilution, sampling) Daily monitoring of cell cultures (cell count, pH) Preparing and executing transfection processes Preparing Benzonase solutions (process additions) Harvesting SUB and clarifying the harvest Sample handling and documentation for USP activities

Downstream Processing (DSP) The DSP department is responsible for the purification of viral vectors using various techniques. The team operates on regular weekday shifts now, but that will change later this year. Core tasks include: Purification using Ion Exchange chromatography Sterile filtration, including

PUPSIT filter integrity testing Ultrafiltration and diafiltration Sample handling and documentation for DSP department

Department: Fill & Finish (F&F) The F&F department performs the final filling and preparation of the product for freezing and storage. The team operates on regular weekday shifts now, but that will change later this year. Key activities include: Preparation of isolators and filling equipment Filling of product in a Grade A isolator Aseptic working in an isolator with an automated filling robot Visual inspection of product vials Labelling of vials and storage of the product in downstream freezers

As a Manufacturing Operator, you will

• Support the installation and operation of new equipment, writing job breakdown sheets for training and work instructions.
• Collaborating in the execution of the daily task and the supporting activities of the department according to procedures and detailed schedule.
• Perform process and GMP documentation activities raise process deviations, notice process gaps, and tackle them, train operators. Contribute to continuous improvement of processes and procedures
• Work safely and compliantly in line with GMP, EHS, and quality standards
• Shifts will apply soon, please ask our recruiter for more information.

Qualifications / Requirements:

• Preferably an MBO 4 or HBO in laboratory & biotechnology, biochemistry, biomedicine, process technology, allround laborant OR equivalent education level with proven experience in biotech or biopharma manufacturing.
• Hands-on expertise in a BSL2 environment, focusing on cell culture, virus propagation, purification, or Fill & Finish, adhering to GMP and EHS standards.
• Strong English communication skills, with the ability to analyse complex situations and maintain high accuracy and independence.
• Adaptable teammate with a proactive approach, ready to tackle challenges and work flexible shifts.

Location: Sassenheim, NL